Presently, clinical reconstruction and repair of bone injuries are realized using allografts and auto-grafts with low success. To avoid complexities related to present treatments, the design and advancement of biomaterial scaffolds to enhance bone restoration has been an aspect of interest in the past years. The necessities for a model biomaterial bone implant are suitable mechanical features, biocompatibility, regulated bio-resorbability, and bioactivity, which encourage bonding between the original tissue and the graft. Polymeric substances enable precise manipulation of properties including architecture, mechanical features, and rate of degradation changing configuration and remodelling method.
The properties may be used to design grafts with the necessary properties for speciï¬c uses. Polymer combinations preserve the flexibility of polymeric scaffolds and incorporate the features of other materials, which may increase bioactivity or mechanical properties. Bio-absorbable or Biodegradable polymers are investigated since their degradation feature indicates that tissues may be deposited in them, however this is a significant design principle for bone recreation, as the mechanical integrity must not be compromised.
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