eurons are essential cells involved in the transmission of messages in the central nervous system (CNS) and peripheral nervous system (PNS). The transmission of the messages is accomplished by networks of neurons forming biological communication networks. Neurotoxins affect neurons, leading to their death or injury. Transected neurons are severed cells with altered chemical and structural ability to transmit impulses along the CNS or the PNS. They lack functional extensions like the axons and dendrites, and the myelin sheaths. It has been demonstrated that most neurotoxins affect the cell bodies of neurons in both the PNS and the CNS. However, some neurotoxins act on the axons of neurons, severing the myelin sheaths surrounding the extensions, but leaving cell bodies intact. In such cases, the neurotoxin leads to chemical transection of the axons. Such axons become biologically isolated from the cell body of the neuron. Research demonstrates that chemically transected axons of the PNS can regenerate while those of the CNS cannot regenerate. Different chemicals have different modes through which chemical transection of neurons is initiated.
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